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Small doses may prove toxic or fatal to a variety of animals and this toxicity is largely influenced the by the mode of the administration of the oil and the nutrition of the animal.

It is a general opinion that the contact of leucorrhoeal matter is a hypoglycemia frequent occasion of the purulent ophthalmia of infants. If there be pressure about the origin of the eighth pair of nerves (or pneumo-gastric nerves,) the respiration always becomes slower; and therefore, when the respiration is less frequent than usual, you should recollect that the metformin affection may be about the head.

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